Description

2-(4-Amino-1-Piperidinyl)Nicotinonitrile (Saltdata: 2Hcl) is a high-purity, advanced pharmaceutical intermediate with a defined dihydrochloride salt form. This compound matters for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), where consistent quality and reliable supply are paramount. It is primarily needed by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology research.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing complex heterocyclic frameworks containing piperidine and pyridine motifs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Applied in the study of biological pathways and as a tool compound for target validation.

Basic Information

Product Name	2-(4-Amino-1-Piperidinyl)Nicotinonitrile (Saltdata: 2Hcl)
CAS No.	412355-86-3
Molecular Formula	C11H15N5 • 2HCl
Molecular Weight	298.19 g/mol (Free base: 217.27 g/mol)
Synonyms	2-(4-Amino-1-piperidinyl)-3-pyridinecarbonitrile dihydrochloride; 2-(4-Aminopiperidin-1-yl)nicotinonitrile dihydrochloride; 3-Cyano-2-(4-aminopiperidin-1-yl)pyridine dihydrochloride; 412355-86-3 (CAS); 2-(4-Amino-piperidin-1-yl)-nicotinonitrile 2HCl; Nicotinonitrile, 2-(4-amino-1-piperidinyl)-, dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Amino-1-Piperidinyl)Nicotinonitrile dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.