Description

1-(5-Bromo-3-Pyridyl)-4-tert-Butoxycarbonylpiperazine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a versatile building block for constructing molecules with specific biological activity. It is primarily utilized by pharmaceutical companies, contract research organizations (CROs), and academic research laboratories focused on drug discovery, particularly in the development of central nervous system (CNS) and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for CNS and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• API Synthesis: Serves as a critical precursor in multi-step synthetic routes for active pharmaceutical ingredients.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing specialized compounds for clients.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening.

Basic Information

Product Name	1-(5-Bromo-3-Pyridyl)-4-tert-Butoxycarbonylpiperazine
CAS No.	412348-60-8
Molecular Formula	C14H20BrN3O2
Molecular Weight	342.23 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)-4-[(1,1-dimethylethoxy)carbonyl]piperazine; 1-Boc-4-(5-bromopyridin-3-yl)piperazine; tert-Butyl 4-(5-bromopyridin-3-yl)piperazine-1-carboxylate; 4-(5-Bromo-3-pyridyl)-1-piperazinecarboxylic acid tert-butyl ester; 1-(5-Bromo-3-pyridyl)piperazine-1-carboxylic acid tert-butyl ester; N-Boc-4-(5-bromo-3-pyridinyl)piperazine; 412348-60-8
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3-Pyridyl)-4-tert-Butoxycarbonylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.