Description

1-(5-Bromo-3-Pyridyl)Piperazine is a high-purity, versatile brominated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and sophisticated agrochemicals, where its specific substitution pattern enables precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex nitrogen-containing target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets and kinase inhibitors.
• Agrochemical Research: Used in developing new-generation herbicides, fungicides, and insecticides that require specific halogenated piperazine motifs.
• Ligand Synthesis: Serves as a building block for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science: A monomer or functionalization agent in the development of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	1-(5-Bromo-3-Pyridyl)Piperazine
CAS No.	412347-30-9
Molecular Formula	C9H12BrN3
Molecular Weight	242.12 g/mol
Synonyms	5-Bromo-3-(1-piperazinyl)pyridine; 3-(Piperazin-1-yl)-5-bromopyridine; 5-Bromo-3-pyridinylpiperazine; 1-(5-Bromo-3-pyridinyl)piperazine; 5-Bromo-3-piperazin-1-ylpyridine; 5-Bromo-3-(piperazin-1-yl)pyridine; 5-Bromopyridin-3-yl-piperazine
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-3-Pyridyl)Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.