Description

(1R,4R)-4-(5-Nitropyridine-2-Ylamino)Cyclohexanol CAS NO 412294-05-4 is a high-purity, chiral organic compound featuring a nitropyridine moiety linked to an aminocyclohexanol scaffold. This molecule is of significant interest as a key pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of potential drug candidates, particularly in therapeutic areas requiring specific stereochemistry.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, or insecticides with targeted activity.
• Ligand Synthesis: The nitropyridine and amino alcohol functional groups make it suitable for constructing complex ligands used in catalysis and metal coordination chemistry.
• Academic & R&D: Employed in chemical research for studying structure-activity relationships (SAR) and developing novel synthetic methodologies.
• Fine Chemical Production: Acts as a specialized intermediate in the multi-step synthesis of dyes, pigments, and other performance chemicals.

Basic Information

Product Name	(1R,4R)-4-(5-Nitropyridine-2-Ylamino)Cyclohexanol
CAS No.	412294-05-4
Molecular Formula	C11H15N3O3
Molecular Weight	237.26 g/mol
Synonyms	(1R,4R)-4-[(5-Nitro-2-pyridinyl)amino]cyclohexanol; 4-[(5-Nitropyridin-2-yl)amino]cyclohexanol (1R,4R)-; (1R,4R)-4-(5-Nitro-2-pyridinylamino)cyclohexanol; (1R,4R)-4-((5-Nitropyridin-2-yl)amino)cyclohexan-1-ol; 2-[[(1R,4R)-4-Hydroxycyclohexyl]amino]-5-nitropyridine; 412294-05-4; (1R,4R)-4-(5-Nitropyridin-2-ylamino)cyclohexanol
EINECS	Contact for details

Quality Control

Our (1R,4R)-4-(5-Nitropyridine-2-Ylamino)Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for research and industrial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.