Description

1-(2,6-Dichloropyridin-3-Yl)Ethanone is a high-purity, synthetically valuable chlorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its primary commercial value lies in enabling the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern is essential for creating molecules with targeted biological activity. This intermediate is particularly sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the dichloropyridine moiety contributes to efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic semiconductors, and other specialty materials requiring a halogenated pyridine core.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), and exploring new synthetic pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis providers and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	1-(2,6-Dichloropyridin-3-Yl)Ethanone
CAS No.	412018-50-9
Molecular Formula	C7H5Cl2NO
Molecular Weight	190.03 g/mol
Synonyms	2',6'-Dichloro-3-acetylpyridine; 3-Acetyl-2,6-dichloropyridine; 1-(2,6-Dichloro-3-pyridinyl)ethanone; Ethanone, 1-(2,6-dichloro-3-pyridinyl)-; 2,6-Dichloro-3-pyridyl methyl ketone; 2,6-Dichloro-3-acetylpyridine; 3-Acetyl-2,6-dichloropyridine
EINECS	Contact for details

Quality Control

Our 1-(2,6-Dichloropyridin-3-Yl)Ethanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, and specifications can be aligned with customer-specific requirements for pharmaceutical (GMP/ICH guidelines) or advanced agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.