Description

Methyl 5-Bromo-8-Hydroxy-1,6-Naphthyridine-7-Carboxylate is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating new heterocyclic compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science Precursor: Serves as a starting material for creating complex organic ligands used in catalysis and functional materials.
• Academic & Contract Research: Employed in university and CRO settings for methodological studies in heterocyclic chemistry and scaffold diversification.
• Chemical Biology Probes: Useful for constructing molecular probes to study biological pathways and protein interactions.

Basic Information

Product Name	Methyl 5-Bromo-8-Hydroxy-1,6-Naphthyridine-7-Carboxylate
CAS No.	410544-37-5
Molecular Formula	C11H7BrN2O3
Molecular Weight	295.09 g/mol
Synonyms	5-Bromo-8-hydroxy-1,6-naphthyridine-7-carboxylic acid methyl ester; Methyl 5-bromo-8-hydroxy-1,6-naphthyridine-7-carboxylate; 7-Methoxycarbonyl-5-bromo-8-hydroxy-1,6-naphthyridine; 1,6-Naphthyridine-7-carboxylic acid, 5-bromo-8-hydroxy-, methyl ester; 410544-37-5
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-8-Hydroxy-1,6-Naphthyridine-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.