Description

7-Bromo-4-Trifluoromethyl-Pyrido[1,2-A]Pyrimidin-2-One is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a bromo substituent and a trifluoromethyl group on a fused pyrido-pyrimidinone scaffold, enabling precise molecular modifications. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrido-pyrimidinone core.
• Material Science: Acts as a building block for creating novel organic electronic materials and specialty polymers with unique properties.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of enzyme inhibitors and receptor ligands for biological studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	7-Bromo-4-Trifluoromethyl-Pyrido[1,2-A]Pyrimidin-2-One
CAS No.	410090-60-7
Molecular Formula	C9H3BrF3N2O
Molecular Weight	292.03 g/mol
Synonyms	7-Bromo-4-(trifluoromethyl)pyrido[1,2-a]pyrimidin-2(1H)-one; 7-Bromo-4-trifluoromethyl-1H-pyrido[1,2-a]pyrimidin-2-one; 410090-60-7; 7-Bromo-4-(trifluoromethyl)-1H-pyrido[1,2-a]pyrimidin-2-one; 7-Bromo-4-(trifluoromethyl)-2H-pyrido[1,2-a]pyrimidin-2-one; 7-Bromo-4-trifluoromethylpyrido[1,2-a]pyrimidin-2-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-4-Trifluoromethyl-Pyrido[1,2-A]Pyrimidin-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.