Description

2-Isocyano-1-Phenylethanole is a versatile isocyanide building block used in organic synthesis. This compound matters for its role as a key precursor in multicomponent reactions, enabling the efficient construction of complex heterocyclic scaffolds and natural product analogs. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of heterocyclic compounds with potential biological activity.
• Agrochemical Research: Used in the discovery and development of new pesticides and herbicides through the creation of unique molecular architectures.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Academic & Industrial R&D: A valuable reagent in multicomponent reactions (MCRs) like the Ugi and Passerini reactions for high-throughput library synthesis and medicinal chemistry.
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological processes and protein interactions.
• Catalyst Ligand Synthesis: Used to prepare novel isocyanide-based ligands for transition metal catalysis.

Basic Information

Product Name	2-Isocyano-1-Phenylethanole
CAS No.	409095-40-5
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	2-Isocyano-1-phenylethanol; 1-Phenyl-2-isocyanoethanol; α-Hydroxybenzyl isocyanide; (2-Isocyanoethyl)benzene alcohol; Isocyanomethyl(phenyl)methanol; NSC 405115; Phenylethanol isocyanide; 2-Isocyano-2-phenylethanol (common misnomer)
EINECS	Contact for details

Quality Control

Our 2-Isocyano-1-Phenylethanole is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.