Description

3-Amino-5-Chloropicolinonitrile is a versatile and high-value heterocyclic building block with significant synthetic utility. Its molecular structure, featuring both amino and nitrile functional groups on a chlorinated pyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. It enables the synthesis of novel active ingredients, particularly in the development of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the development of advanced organic materials, such as organic semiconductors and liquid crystals, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Amino-5-Chloropicolinonitrile
CAS No.	408538-29-4
Molecular Formula	C6H4ClN3
Molecular Weight	153.57 g/mol
Synonyms	5-Chloro-3-aminopicolinonitrile; 3-Amino-5-chloro-2-cyanopyridine; 5-Chloro-3-aminopyridine-2-carbonitrile; 2-Cyano-5-chloropyridin-3-amine; 3-Amino-5-chloro-2-pyridinecarbonitrile; 5-Chloro-2-cyanopyridin-3-amine; 3-Amino-5-chloropicolinonitrile; 5-Chloro-3-pyridinamine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Chloropicolinonitrile is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in the fine chemical and pharmaceutical sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.