Description

(6-tert-Butoxycarbonylamino-Pyridin-2-Yl)-Acetic Acid CAS NO 408367-22-6 is a high-purity, protected amino acid derivative featuring a pyridine core and a Boc-protected amine group. This compound is a critical building block in modern pharmaceutical synthesis, enabling the controlled introduction of functionalized pyridine motifs into complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Peptide Mimetics Development: Used to incorporate heterocyclic, rigidified structures into peptide backbones to enhance stability and biological activity.
• Agrochemical Synthesis: Serves as a precursor in the creation of advanced herbicides and fungicides with specific targeting properties.
• Ligand and Catalyst Design: Employed in the preparation of specialized ligands for metal catalysis and organocatalysis.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds under cGMP conditions.

Basic Information

Product Name	(6-tert-Butoxycarbonylamino-Pyridin-2-Yl)-Acetic Acid
CAS No.	408367-22-6
Molecular Formula	C₁₃H₁₈N₂O₄
Molecular Weight	266.29 g/mol
Synonyms	2-[(6-{[(tert-Butoxy)carbonyl]amino}pyridin-2-yl)]acetic Acid; (6-Boc-amino-2-pyridyl)acetic Acid; 2-(6-((tert-Butoxycarbonyl)amino)pyridin-2-yl)acetic Acid; N-Boc-6-amino-2-pyridineacetic Acid; Boc-6-A-2-PAA; 408367-22-6; 2-Pyridineacetic acid, 6-[[(1,1-dimethylethoxy)carbonyl]amino]-
EINECS	Contact for details

Quality Control

Our (6-tert-Butoxycarbonylamino-Pyridin-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes. We support development and commercial projects requiring compliance with cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.