Description

(3-Hydroxymethyl-Pyridin-4-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, protected intermediate of significant value in advanced organic synthesis. Its core utility lies in serving as a versatile building block for the construction of complex nitrogen-containing heterocycles, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its pyridine-based structure.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Peptidomimetic Chemistry: The protected carbamate and hydroxymethyl groups make it valuable for constructing peptide-like molecules with enhanced stability.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	(3-Hydroxymethyl-Pyridin-4-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	407623-72-7
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	tert-Butyl N-(3-hydroxymethyl-4-pyridyl)carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-pyridinemethanol; 3-(Hydroxymethyl)-N-Boc-4-aminopyridine; N-Boc-3-hydroxymethyl-4-aminopyridine; 4-Amino-3-pyridinemethanol, N-Boc derivative; Boc-4-Amino-3-pyridinemethanol; (3-Hydroxymethyl-4-pyridinyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (3-Hydroxymethyl-Pyridin-4-Yl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.