Description

(2-Oxo-Cyclobutyl)-Carbamic Acid Benzyl Ester is a high-purity, specialized organic building block of significant interest in advanced synthetic chemistry. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and complex bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in custom synthesis and process development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of new active pharmaceutical ingredients (APIs), particularly those containing cyclobutane or β-lactam-like scaffolds.
• Protease Inhibitor Research: Used in the development of enzyme inhibitors, where the (2-oxo-cyclobutyl)carbamate moiety can mimic transition states or serve as a covalent warhead.
• Peptidomimetic Chemistry: Employed as a constrained, non-natural amino acid derivative for constructing peptide analogs with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, or insecticides with unique modes of action.
• Material Science Precursor: Potential use in synthesizing specialized polymers or dendrimers with tailored functional properties.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes (ABPs) for studying enzyme function and target engagement.

Basic Information

Product Name	(2-Oxo-Cyclobutyl)-Carbamic Acid Benzyl Ester
CAS No.	406951-43-7
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	Benzyl (2-oxocyclobutyl)carbamate; Carbamic acid, (2-oxocyclobutyl)-, benzyl ester; N-(2-Oxocyclobutyl)carbamic Acid Benzyl Ester; 2-Oxocyclobutylcarbamic Acid Benzyl Ester; O-Benzyl (2-oxocyclobutyl)carbamate; Benzyl 2-oxocyclobutylcarbamate; (2-Oxocyclobutyl)carbamic Acid Phenylmethyl Ester
EINECS	Contact for details

Quality Control

Our (2-Oxo-Cyclobutyl)-Carbamic Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.