Description

3-Chloro-5,6-Difluoropicolinic Acid is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique halogenated picolinate structure, which serves as a critical intermediate in the development of complex molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting complex heterocycles.
• Agrochemical Research: Serves as a versatile precursor in the development of next-generation herbicides and plant growth regulators, leveraging its halogenated pyridine core.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs) due to its carboxylic acid and halogen functionalities.
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Custom Synthesis & Contract Manufacturing: An important building block for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	3-Chloro-5,6-Difluoropicolinic Acid
CAS No.	406676-40-2
Molecular Formula	C6H2ClF2NO2
Molecular Weight	193.54 g/mol
Synonyms	3-Chloro-5,6-difluoropyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 3-chloro-5,6-difluoro-; 5,6-Difluoro-3-chloropicolinic acid; 3-Chloro-5,6-difluoropicolinate; Picolinic acid, 3-chloro-5,6-difluoro-; 3-Chloro-5,6-difluoro-2-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6-Difluoropicolinic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.