Description

3,5-Dichloro-2-Fluoro-6-Iodopyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile and valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Ligand Synthesis: Intermediate for the preparation of sophisticated nitrogen-containing ligands used in catalysis.
• Chemical Biology Probes: Used to synthesize molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	3,5-Dichloro-2-Fluoro-6-Iodopyridine
CAS No.	406676-35-5
Molecular Formula	C5HCl2FIN
Molecular Weight	291.87 g/mol
Synonyms	2-Fluoro-3,5-dichloro-6-iodopyridine; 6-Iodo-3,5-dichloro-2-fluoropyridine; 3,5-Dichloro-2-fluoro-6-iodopyridine; Pyridine, 3,5-dichloro-2-fluoro-6-iodo-; 406676-35-5; CAS 406676-35-5
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dichloro-2-Fluoro-6-Iodopyridine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.