Description

3,5-Dichloro-2-Fluoro-4-Iodopyridine is a high-purity halogenated pyridine derivative, a crucial advanced intermediate in modern synthetic chemistry. Its unique substitution pattern makes it a versatile and valuable building block for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated and iodinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen atoms contribute to biological activity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in cross-coupling and other metal-mediated reactions.
• Material Science Research: Employed in the synthesis of functionalized organic materials and liquid crystals, leveraging its halogenated pyridine core.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for imaging and diagnostic applications due to the presence of the iodine atom.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3,5-Dichloro-2-Fluoro-4-Iodopyridine
CAS No.	406676-24-2
Molecular Formula	C5HCl2FIN
Molecular Weight	291.87 g/mol
Synonyms	2-Fluoro-3,5-dichloro-4-iodopyridine; 4-Iodo-3,5-dichloro-2-fluoropyridine; 3,5-Dichloro-2-fluoro-4-iodopyridine; Pyridine, 3,5-dichloro-2-fluoro-4-iodo-; 406676-24-2; 2-Fluoro-4-iodo-3,5-dichloropyridine
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2-Fluoro-4-Iodopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.