Description

Carbamic Acid, [(3R)-Tetrahydro-4-Oxo-3-Furanyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, chiral chemical intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a key protected building block for the construction of complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of novel protease inhibitors, a major class of therapeutic agents.
• Asymmetric Synthesis: Serves as a protected, enantiomerically pure starting material for constructing stereogenic centers in complex organic molecules.
• Peptidomimetics & Bioactive Molecules: Integral for the synthesis of peptidomimetic compounds and other bioactive small molecules in medicinal chemistry programs.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of target molecules.
• Academic & Industrial R&D: A valuable reagent for research laboratories in universities and pharmaceutical companies exploring new chemical entities.

Basic Information

Product Name	Carbamic Acid, [(3R)-Tetrahydro-4-Oxo-3-Furanyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	406220-17-5
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(R)-3-((tert-Butoxycarbonyl)amino)dihydrofuran-2(3H)-one; (3R)-3-[(tert-Butoxycarbonyl)amino]tetrahydrofuran-2-one; tert-Butyl N-[(3R)-2-oxooxolan-3-yl]carbamate; (R)-3-(Boc-amino)butyrolactone; Boc-DL-Homoserine Lactone (enantiomer); (R)-3-(Boc-amino)dihydro-2(3H)-furanone; (R)-N-Boc-3-aminodihydrofuran-2-one
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(3R)-Tetrahydro-4-Oxo-3-Furanyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.