Description

Benzyl (6-Amino-5-Bromopyridin-3-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct pyridine core functionalized with amino, bromo, and carbamate protecting groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to its reactive bromo and amino groups.
• Research & Development: Essential for medicinal chemists in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Agrochemical Synthesis: Potential use in creating novel compounds for crop protection research.
• Chemical Biology Probes: Can be used to develop molecular probes for studying biological pathways and target engagement.

Basic Information

Product Name	Benzyl (6-Amino-5-Bromopyridin-3-Yl)Carbamate
CAS No.	405939-48-2
Molecular Formula	C13H12BrN3O2
Molecular Weight	322.16 g/mol
Synonyms	Carbamic acid, N-(6-amino-5-bromo-3-pyridinyl)-, phenylmethyl ester; Benzyl N-(6-amino-5-bromopyridin-3-yl)carbamate; 5-Bromo-3-(((benzyloxy)carbonyl)amino)pyridin-2-amine; (6-Amino-5-bromopyridin-3-yl)carbamic acid benzyl ester; BOC-6-Amino-5-Bromopyridine-3-Carbamate (common abbreviation); Benzyl 6-Amino-5-Bromo-3-pyridylcarbamate
EINECS	Contact for details

Quality Control

Our Benzyl (6-Amino-5-Bromopyridin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.