Description

(4-Iodo-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is a high-value, protected heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic placement of the iodine atom and the Boc-protected amine, enabling precise cross-coupling reactions and subsequent deprotection for further functionalization. This compound is critically needed by pharmaceutical and agrochemical R&D teams for constructing complex pyridine-based molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides that require functionalized pyridine cores.
• Material Science Research: Serves as a building block for creating specialized ligands, catalysts, and organic electronic materials.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Item	Details
Product Name	(4-Iodo-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	405939-28-8
Molecular Formula	C10H13IN2O2
Molecular Weight	320.13 g/mol
Synonyms	tert-Butyl (4-iodopyridin-2-yl)carbamate; N-Boc-4-iodopyridin-2-amine; 2-((tert-Butoxycarbonyl)amino)-4-iodopyridine; Boc-4-Iodo-2-aminopyridine; 4-Iodo-2-pyridinamine, N-[(1,1-dimethylethoxy)carbonyl]-; 405939-28-8; (4-Iodo-2-pyridinyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of (4-Iodo-Pyridin-2-Yl)-Carbamic Acid tert-Butyl Ester is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.