Description

n-(2,2,2-Trifluoroethyl)Benzeneethanamine Hydrochloride is a high-purity, specialized organic salt compound that serves as a critical building block in advanced chemical synthesis. Its value lies in the unique trifluoroethylamine moiety, which is instrumental in modulating the physicochemical and metabolic properties of target molecules. This intermediate is primarily needed by research and development teams within the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, due to the fluorine-containing group's ability to enhance blood-brain barrier penetration and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoroethyl group can improve biological activity and environmental persistence profiles.
• Fluorinated Compound Synthesis: Serves as a versatile precursor for introducing the -CH2CF3 group into more complex molecular architectures in medicinal and material chemistry.
• Chemical Biology & Proteomics: Employed in the design of chemical probes and affinity tags for studying enzyme function and protein-protein interactions.
• Ligand Development: Useful in creating novel ligands for catalysis or receptor binding studies in both academic and industrial research settings.

Basic Information

Product Name	n-(2,2,2-Trifluoroethyl)Benzeneethanamine Hydrochloride
CAS No.	405879-06-3
Molecular Formula	C10H13ClF3N
Molecular Weight	239.66 g/mol
Synonyms	2-(2,2,2-Trifluoroethylamino)ethylbenzene hydrochloride; N-(2,2,2-Trifluoroethyl)phenethylamine hydrochloride; 2-Phenylethyl(2,2,2-trifluoroethyl)amine hydrochloride; 1-Phenyl-2-[(2,2,2-trifluoroethyl)amino]ethane hydrochloride; Benzeneethanamine, N-(2,2,2-trifluoroethyl)-, hydrochloride; α-Phenethyl-2,2,2-trifluoroethylamine HCl; (2-Phenylethyl)(2,2,2-trifluoroethyl)ammonium chloride
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoroethyl)Benzeneethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.