Description

3-Piperidinecarboxylicacid,5-Methyl-,Methylester,(3S,5R)-(9Ci) is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical synthesis. Its defined stereochemistry at the 3S and 5R positions makes it an invaluable intermediate for creating enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) agents and metabolic disease treatments.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug molecules targeting specific biological pathways.
• CNS Drug Research: Used in the development of potential neuroactive compounds, including receptor modulators and enzyme inhibitors.
• Metabolic Disorder Therapeutics: Serves as a precursor in the creation of candidates for treating diabetes, obesity, and related conditions.
• Asymmetric Catalysis Ligand Precursor: Its structure can be modified to form ligands for chiral catalysts used in stereoselective chemical reactions.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) explorations to optimize the potency and selectivity of lead compounds.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for API manufacturing under cGMP.

Basic Information

Product Name	3-Piperidinecarboxylicacid,5-Methyl-,Methylester,(3S,5R)-(9Ci)
CAS No.	405513-12-4
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(3S,5R)-5-Methylpiperidine-3-carboxylic acid methyl ester; Methyl (3S,5R)-5-methylnipecotate; (3S,5R)-Methyl 5-methylpiperidine-3-carboxylate; 5-Methylnipecotic acid methyl ester, (3S,5R)-; (3S,5R)-5-Methyl-3-piperidinecarboxylic acid methyl ester; Methyl (3S,5R)-5-methyl-3-piperidinecarboxylate; (3S,5R)-5-Methyl-3-piperidinecarboxylic acid, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Piperidinecarboxylicacid,5-Methyl-,Methylester,(3S,5R)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for advanced research and pharmaceutical development. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.