Description

6-[(4-Methylpyridin-2-Yl)Amino]-6-Oxohexanoic Acid is a high-purity organic compound featuring a pyridine core linked to a hexanoic acid chain via an amide bond. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Serves as a crucial building block for constructing compound libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Bioconjugation & Probe Development: The carboxylic acid and amide functionalities allow for conjugation to biomolecules, useful in creating diagnostic probes or targeted therapeutics.
• Chemical Biology Studies: Employed as a tool compound to investigate specific biological interactions and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Item	Detail
Product Name	6-[(4-Methylpyridin-2-Yl)Amino]-6-Oxohexanoic Acid
CAS No.	405270-96-4
Molecular Formula	C₁₃H₁₈N₂O₃
Molecular Weight	250.29 g/mol
Synonyms	6-[(4-Methyl-2-pyridinyl)amino]-6-oxohexanoic acid; 6-Oxo-6-[(4-methylpyridin-2-yl)amino]hexanoic acid; 4-Methyl-2-[(5-carboxypentanoyl)amino]pyridine; N-(4-Methylpyridin-2-yl)adipamic acid; Adipamic acid, N-(4-methyl-2-pyridinyl)-; 405270-96-4; (4-Methylpyridin-2-yl)carbamic acid 5-carboxypentyl ester (tautomeric form)
EINECS	Contact for details

Quality Control

Our 6-[(4-Methylpyridin-2-Yl)Amino]-6-Oxohexanoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.