Description

2,5-Dichloropyridine-3,4-Diamine is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive amine and halogen substituents, which enable precise functionalization and the construction of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and kinase inhibitors.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the pyridine core provides favorable biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Functional Material Precursor: Employed in the research and production of organic electronic materials, such as charge-transport layers and light-emitting components.
• Dye and Pigment Chemistry: Acts as a building block for synthesizing specialized heterocyclic dyes and pigments with specific color and stability properties.
• Cross-Coupling Reactions: The chlorine atoms make it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl and amino-substituted structures.

Basic Information

Product Name	2,5-Dichloropyridine-3,4-Diamine
CAS No.	405230-94-6
Molecular Formula	C5H5Cl2N3
Molecular Weight	178.02 g/mol
Synonyms	3,4-Diamino-2,5-dichloropyridine; 2,5-Dichloro-3,4-pyridinediamine; 2,5-Dichloro-3,4-diaminopyridine; 3,4-Pyridinediamine, 2,5-dichloro-; 2,5-Dichloropyridine-3,4-diyldiamine; 2,5-Dichloro-3,4-diamino pyridine; 2,5-Dichloro-4-aminopyridin-3-amine
EINECS	Contact for details

Quality Control

Our 2,5-Dichloropyridine-3,4-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.