Description

2-Chloro-5-Fluoro-3-Nitro-4-Pyridinamine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated and nitro-substituted pyridine core makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyridine structure for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for introducing chloro, fluoro, and nitro functional groups into more complex heterocyclic compounds.
• Material Science Research: Investigated as a monomer or precursor for the synthesis of specialized polymers and functional materials with unique electronic properties.
• Dye and Pigment Intermediate: Utilized in the research and development of novel dyes, pigments, and photographic chemicals.

Basic Information

Product Name	2-Chloro-5-Fluoro-3-Nitro-4-Pyridinamine
CAS No.	405230-90-2
Molecular Formula	C5H4ClFN3O2
Molecular Weight	191.56 g/mol
Synonyms	4-Amino-2-chloro-5-fluoro-3-nitropyridine; 2-Chloro-5-fluoro-3-nitro-4-pyridinamine; 4-Pyridinamine, 2-chloro-5-fluoro-3-nitro-; 2-Chloro-5-fluoro-3-nitropyridin-4-amine; 5-Fluoro-2-chloro-3-nitro-4-aminopyridine; 3-Nitro-2-chloro-5-fluoro-4-aminopyridine; 4-Amino-2-chloro-5-fluoro-3-nitropyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-3-Nitro-4-Pyridinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the nitro and amine functional groups, it should be stored separately from strong oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.