Description

2,3,6-Trifluoro-5-Nitropyridin-4-Amine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoro-nitro-amine substitution pattern makes it an indispensable intermediate for creating complex molecules with tailored electronic and biological properties. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and kinase inhibitors.
• Agrochemical Synthesis: Building block for developing next-generation herbicides and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Material Science Research: Used in the development of organic electronic materials, such as electron-transport layers for OLEDs, due to its electron-deficient aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Studies: A valuable substrate for studying nucleophilic aromatic substitution (SNAr) reactions and other transformations on highly fluorinated heterocycles.
• Dye and Pigment Intermediate: Potential use in creating specialized fluorinated dyes and pigments with unique colorfastness and spectral properties.

Basic Information

Product Name	2,3,6-Trifluoro-5-Nitropyridin-4-Amine
CAS No.	405230-88-8
Molecular Formula	C5H2F3N3O2
Molecular Weight	193.08 g/mol
Synonyms	4-Amino-2,3,6-trifluoro-5-nitropyridine; 5-Nitro-2,3,6-trifluoropyridin-4-amine; 2,3,6-Trifluoro-5-nitro-4-pyridinamine; 4-Pyridinamine, 2,3,6-trifluoro-5-nitro-; 2,3,6-Trifluoro-5-nitropyridin-4-ylamine; 5-Nitro-2,3,6-trifluoro-4-aminopyridine; TFNP-4-Amine
EINECS	Contact for details

Quality Control

Our production of 2,3,6-Trifluoro-5-Nitropyridin-4-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.