Description

Pyridine, 2-Chloro-5-Fluoro-, 1-Oxide (9Ci) is a halogenated pyridine N-oxide derivative, a versatile and highly functionalized heterocyclic building block. This compound is valued for its unique reactivity, particularly in facilitating nucleophilic aromatic substitution reactions, which are crucial for constructing complex molecular architectures. It serves as a key synthetic intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, enabling the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing fluorinated and chlorinated heterocycles.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the halogen and N-oxide functionalities impart specific biological activity.
• Material Science Research: Employed as a building block for creating novel ligands, catalysts, and functional organic materials.
• Chemical Synthesis: Facilitates challenging coupling and functionalization reactions in medicinal and process chemistry due to its activated pyridine ring.
• Life Science Reagents: Used in the preparation of biochemical probes, fluorescent markers, and other research compounds.

Basic Information

Product Name	Pyridine, 2-Chloro-5-Fluoro-, 1-Oxide (9Ci)
CAS No.	405230-79-7
Molecular Formula	C5H3ClFNO
Molecular Weight	147.54 g/mol
Synonyms	2-Chloro-5-fluoropyridine 1-oxide; 2-Chloro-5-fluoropyridine N-oxide; 5-Fluoro-2-chloropyridine 1-oxide; 2-Chloro-5-fluoropyridine oxide; 2-Chloro-5-fluoropyridin-1-ium-1-olate; 2-Chloro-5-fluoro-1-oxidopyridin-1-ium
EINECS	Contact for details

Quality Control

Our Pyridine, 2-Chloro-5-Fluoro-, 1-Oxide (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.