Description

5-Bromo-2-Chloro-3-Cyanopyridine is a high-purity, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogen and nitrile groups for bioactivity.
• Ligand and Catalyst Development: Serves as a versatile scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive compounds for OLEDs.
• Chemical Biology Probe: Useful for designing molecular probes and tags due to its reactive handles for bioconjugation.
• Custom Synthesis and R&D: A valuable starting material for contract research organizations (CROs) and academic labs exploring new chemical space.

Basic Information

Product Name	5-Bromo-2-Chloro-3-Cyanopyridine
CAS No.	405224-23-9
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	2-Chloro-5-bromo-3-cyanopyridine; 3-Cyano-5-bromo-2-chloropyridine; 5-Bromo-2-chloronicotinonitrile; 2-Chloro-5-bromonicotinonitrile; 3-Pyridinecarbonitrile, 5-bromo-2-chloro-; 405224-23-9; 5-Br-2-Cl-3-CN-Pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-3-Cyanopyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.