Description

6-Methoxy-5-(Trifluoromethyl)Pyridin-2-Amine is a high-value pyridine derivative building block, distinguished by its methoxy and trifluoromethyl substituents which impart unique electronic and steric properties. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its structural motifs are leveraged to modulate bioactivity and metabolic stability. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Precursor: Serves as a building block for functionalized ligands and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development and the synthesis of complex heterocyclic compounds.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, high-purity pyridine derivatives.

Basic Information

Product Name	6-Methoxy-5-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	405160-57-8
Molecular Formula	C7H7F3N2O
Molecular Weight	192.14 g/mol
Synonyms	2-Amino-6-methoxy-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-6-methoxypyridin-2-amine; 6-Methoxy-5-trifluoromethylpyridin-2-amine; 2-Pyridinamine, 6-methoxy-5-(trifluoromethyl)-; 405160-57-8; 6-Methoxy-5-(trifluoromethyl)-2-pyridinamine
EINECS	Contact for details

Quality Control

Our 6-Methoxy-5-(Trifluoromethyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and production use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.