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2,4-Dichloro-3-Methoxypyridine CAS NO 405143-46-6


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CAS No.:405143-46-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,4-Dichloro-3-Methoxypyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its reactive chlorine atoms and methoxy substituent, which enable precise functionalization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel compounds.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drug candidates targeting central nervous system and anti-infective applications.
  • Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
  • Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and specialty polymers.
  • Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry, enabling structure-activity relationship (SAR) studies and route scouting.
  • Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for clients.

Basic Information

Product Name 2,4-Dichloro-3-Methoxypyridine
CAS No. 405143-46-6
Molecular Formula C6H5Cl2NO
Molecular Weight 178.02 g/mol
Synonyms 3-Methoxy-2,4-dichloropyridine; 2,4-Dichloro-3-methoxypyridine; 2,4-Dichloro-3-pyridinol methyl ether; Pyridine, 2,4-dichloro-3-methoxy-
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Quality Control

Our 2,4-Dichloro-3-Methoxypyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and relevant ICH guidelines ensures a reliable supply for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Melting Point Contact for details
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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