Description

4-Hydroxy-2-Iodo-3-Methoxypyridine is a versatile halogenated pyridine derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its unique substitution pattern, which provides reactive sites for further functionalization, enabling the construction of complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, leveraging its halogen and methoxy functional groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials, organic light-emitting diodes (OLEDs), and liquid crystals.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes due to the reactivity of the iodine atom.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	4-Hydroxy-2-Iodo-3-Methoxypyridine
CAS No.	405137-17-9
Molecular Formula	C6H6INO2
Molecular Weight	250.02 g/mol
Synonyms	3-Methoxy-2-iodopyridin-4-ol; 2-Iodo-3-methoxy-4-pyridinol; 4-Pyridinol, 2-iodo-3-methoxy-; 2-Iodo-3-methoxypyridin-4(1H)-one (tautomer); 4-Hydroxy-2-iodo-3-methoxypyridine; 405137-17-9 (CAS); Halogenated pyridine derivative; Iodomethoxypyridinol
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Iodo-3-Methoxypyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.