Description

3-Pyridinecarboxylic Acid, 2-(1-Hydroxyethyl)- (9Ci) is a specialized pyridine derivative that serves as a high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a carboxylic acid and a chiral hydroxyethyl substituent, makes it a critical building block for constructing complex molecules with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific stereochemical configurations for optimal activity.
• Chiral Ligand & Catalyst Development: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research & Development: A valuable building block in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Employed in the manufacture of high-purity, specialty chemicals for electronics and material science applications.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2-(1-Hydroxyethyl)- (9Ci)
CAS No.	405111-47-9
Molecular Formula	C8H9NO3
Molecular Weight	167.16 g/mol
Synonyms	2-(1-Hydroxyethyl)nicotinic Acid; 2-(1-Hydroxyethyl)-3-pyridinecarboxylic Acid; (2-Hydroxyethyl)nicotinic Acid (related isomer); 2-(α-Hydroxyethyl)nicotinic Acid; 2-(1-Hydroxyethyl)pyridine-3-carboxylic Acid; Nicotinic Acid, 2-(1-hydroxyethyl)-; CAS 405111-47-9
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our standard grade for this intermediate typically meets a purity specification of ≥97% (by HPLC), with stringent control of related substances and chiral purity where applicable. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with every shipment. We can support development projects with material produced under GMP-like conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccant packs or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.