Description

3-Butyn-2-Ol, 4-(2-Pyridinyl)-, (2S)- (9Ci) is a chiral, high-purity chemical building block featuring a pyridine-substituted butynol structure. This compound is valued for its role as a key synthetic intermediate in the development of complex, biologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and herbicides that require specific stereochemistry for efficacy.
• Ligand Precursor: Serves as a starting material for the synthesis of specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways involving alkynes and heterocycles.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty materials where optical purity is critical.

Basic Information

Product Name	3-Butyn-2-Ol, 4-(2-Pyridinyl)-, (2S)- (9Ci)
CAS No.	405065-81-8
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	(2S)-4-(Pyridin-2-yl)but-3-yn-2-ol; (S)-4-(2-Pyridinyl)-3-butyn-2-ol; 4-(2-Pyridinyl)-3-butyn-2-ol, (2S)-; (S)-4-(Pyridin-2-yl)but-3-yn-2-ol; 405065-81-8; (2S)-4-(2-Pyridinyl)-3-butyn-2-ol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques including chiral HPLC, NMR, and GC/MS to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) are available upon request, providing full transparency on all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.