Description

tert-Butyl Methyl(1-(Pyridin-3-Yl)Piperidin-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is essential for medicinal chemistry research, process development, and scale-up manufacturing within the global pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry & Scale-Up: Serves as a defined starting material for the development and validation of robust, scalable synthetic routes under GMP conditions.
• API Manufacturing: Incorporated into the final synthetic steps for producing target active pharmaceutical ingredients requiring this specific piperidine-pyridine scaffold.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	tert-Butyl Methyl(1-(Pyridin-3-Yl)Piperidin-4-Yl)Carbamate
CAS No.	405058-03-9
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	1-Boc-4-(N-Methyl-N-(3-pyridyl)amino)piperidine; tert-Butyl 4-[Methyl(3-pyridinyl)amino]-1-piperidinecarboxylate; 4-[Methyl(pyridin-3-yl)amino]piperidine-1-carboxylic acid tert-butyl ester; N-Boc-N'-Methyl-N'-(3-pyridyl)-4-aminopiperidine; Methyl(1-(pyridin-3-yl)piperidin-4-yl)carbamic acid tert-butyl ester; 405058-03-9; BOC-4-(N-Methyl-N-3-pyridylamino)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl Methyl(1-(Pyridin-3-Yl)Piperidin-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.