Description

o-(tert-Butyldimethylsilyl)Benzanilide is a specialized organosilicon-protected anilide derivative, serving as a crucial synthetic intermediate in advanced organic synthesis. Its primary value lies in its role as a protected amine precursor, enabling complex multi-step reactions where selective deprotection is required. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those containing aniline or benzanilide motifs.
• Peptidomimetic Research: Used in the preparation of peptide analogs and constrained scaffolds where the tert-butyldimethylsilyl (TBDMS) group protects sensitive functionalities.
• Agrochemical Synthesis: Intermediate for creating novel herbicides, fungicides, and insecticides that require protected aniline derivatives.
• Material Science: Potential monomer or modifier in the synthesis of specialized polymers and advanced organic materials.
• Academic & R&D: A valuable reagent for methodological development in synthetic organic chemistry, particularly in studies involving silicon-based protecting groups.

Basic Information

Product Name	o-(tert-Butyldimethylsilyl)Benzanilide
CAS No.	404392-70-7
Molecular Formula	C19H25NOSi
Molecular Weight	311.50 g/mol
Synonyms	N-Phenyl-2-[(tert-butyldimethylsilyl)oxy]benzamide; 2-[(tert-Butyldimethylsilyl)oxy]-N-phenylbenzamide; Benzanilide, o-(tert-butyldimethylsilyl)-; o-TBDMS Benzanilide; 2-(Tert-butyldimethylsiloxy)-N-phenylbenzamide; N-Phenyl-o-(tert-butyldimethylsilyloxy)benzamide
EINECS	Contact for details

Quality Control

Our o-(tert-Butyldimethylsilyl)Benzanilide is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Quality is verified through a suite of analytical techniques including HPLC, NMR, and GC. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.