Description

1-[(6-Fluoro-2-Naphthalenyl)Methyl]-Piperidine-4-Carboxylic Acid is a high-value, fluorinated naphthalene-piperidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular architecture, featuring a fused aromatic system and a functionalized piperidine ring, makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and specialty materials. This compound is primarily targeted at research and development teams within the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate complex, fluorinated heterocyclic motifs into their molecular designs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the naphthalene and piperidine structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated as a monomer or additive for developing polymers with specific optical or electronic properties.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific fluorinated scaffold.

Basic Information

Product Name	1-[(6-Fluoro-2-Naphthalenyl)Methyl]-Piperidine-4-Carboxylic Acid
CAS No.	403479-29-8
Molecular Formula	C17H18FNO2
Molecular Weight	287.33 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-[(6-fluoro-2-naphthalenyl)methyl]-; 1-[(6-Fluoronaphthalen-2-yl)methyl]piperidine-4-carboxylic acid; 403479-29-8; 6-Fluoro-2-naphthalenemethyl piperidine-4-carboxylate; Fluoronaphthylmethyl piperidinecarboxylic acid; FNMPCA (abbrev.); 1-((6-Fluoro-2-naphthyl)methyl)isonipecotic acid
EINECS	Contact for details

Quality Control

Our production of 1-[(6-Fluoro-2-Naphthalenyl)Methyl]-Piperidine-4-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.