Description

Cyclopenta[C]Pyrrole-1-Carboxylic Acid, Octahydro-4-Hydroxy-, Ethyl Ester, (1S,3Ar,6As)- (9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound matters as a critical chiral building block for the synthesis of complex active pharmaceutical ingredients (APIs), where its specific stereochemistry is essential for biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of proprietary drug candidates, especially those targeting the central nervous system or metabolic diseases.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities based on the fused cyclopentapyrrole scaffold.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Asymmetric Synthesis: Utilized in catalytic or stoichiometric asymmetric transformations to construct complex molecular architectures due to its pre-defined stereocenters.
• Reference Standard: Acts as an analytical standard for quality control and method validation in API manufacturing processes.

Basic Information

Product Name	Cyclopenta[C]Pyrrole-1-Carboxylic Acid, Octahydro-4-Hydroxy-, Ethyl Ester, (1S,3Ar,6As)- (9Ci)
CAS No.	402958-79-6
Molecular Formula	C10H17NO3
Molecular Weight	199.25 g/mol
Synonyms	(1S,3aR,6aS)-Octahydro-4-hydroxycyclopenta[c]pyrrole-1-carboxylic acid ethyl ester; Ethyl (1S,3aR,6aS)-octahydro-4-hydroxy-1H-cyclopenta[c]pyrrole-1-carboxylate; 1H-Cyclopenta[c]pyrrole-1-carboxylic acid, octahydro-4-hydroxy-, ethyl ester, (1S,3aR,6aS)-; 402958-79-6; (1S,3aR,6aS)-Ethyl 4-hydroxyoctahydro-1H-cyclopenta[c]pyrrole-1-carboxylate
EINECS	Contact for details

Quality Control

Our Cyclopenta[C]Pyrrole-1-Carboxylic Acid, Octahydro-4-Hydroxy-, Ethyl Ester, (1S,3Ar,6As)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.