Description

1-Pyrrolidinecarboxylic Acid, 2-Methyl-5-Oxo-, 1,1-Dimethylethyl Ester, (2R)- is a high-value, chiral proline derivative that serves as a critical building block in modern organic synthesis. Its significance lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of protease inhibitors, antiviral drugs, and other complex APIs requiring a defined (R)-configured proline scaffold.
• Peptidomimetics Research: Used to introduce constrained proline analogs into peptide backbones to enhance metabolic stability and biological activity.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective transformations.
• Agrochemical Synthesis: Employed in the development of advanced herbicides and fungicides with improved efficacy and environmental profiles.
• Fine Chemical Production: A versatile intermediate for manufacturing specialty chemicals, flavors, and fragrances.
• Academic & R&D Laboratories: Used in methodological development and the discovery of new synthetic routes for complex organic molecules.

Basic Information

Product Name	1-Pyrrolidinecarboxylic Acid, 2-Methyl-5-Oxo-, 1,1-Dimethylethyl Ester, (2R)-
CAS No.	402955-77-5
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(R)-tert-Butyl 2-methyl-5-oxopyrrolidine-1-carboxylate; (R)-1-Boc-2-methyl-5-pyrrolidinone; (2R)-2-Methyl-5-oxo-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester; (R)-1-(tert-Butoxycarbonyl)-2-methyl-5-pyrrolidinone; tert-Butyl (R)-2-methyl-5-oxopyrrolidine-1-carboxylate; (R)-Boc-2-methyl-5-oxopyrrolidine; (R)-N-Boc-2-methyl-5-pyrrolidinone; (2R)-1-(tert-Butoxycarbonyl)-2-methylpyrrolidin-5-one
EINECS	Contact for details

Quality Control

Our production of 1-Pyrrolidinecarboxylic Acid, 2-Methyl-5-Oxo-, 1,1-Dimethylethyl Ester, (2R)- adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting industry standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.