Description

tert-Butyl [6-(2-Hydroxyethyl)Pyridin-2-Yl]Carbamate is a high-purity, protected amino alcohol derivative featuring a pyridine core. This compound is a critical pharmaceutical intermediate and versatile organic building block for advanced synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules, particularly in medicinal chemistry programs targeting novel therapeutics.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule drugs.
• Medicinal Chemistry Building Block: Used in drug discovery for structure-activity relationship (SAR) studies and lead optimization due to its modifiable hydroxyethyl and protected carbamate functionalities.
• Agrochemical Synthesis: Intermediate in the development of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetic Research: Employed in the design and synthesis of peptide analogs and conformationally restricted scaffolds.
• Chemical Biology Probes: Useful for synthesizing labeled compounds or probes for studying biological pathways and target engagement.

Basic Information

Product Name	tert-Butyl [6-(2-Hydroxyethyl)Pyridin-2-Yl]Carbamate
CAS No.	402933-56-6
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	tert-Butyl 6-(2-hydroxyethyl)pyridin-2-ylcarbamate; 2-[(tert-Butoxycarbonyl)amino]-6-(2-hydroxyethyl)pyridine; 2-(6-((tert-Butoxycarbonyl)amino)pyridin-2-yl)ethanol; 6-(2-Hydroxyethyl)-2-pyridinylcarbamic Acid 1,1-Dimethylethyl Ester; N-Boc-6-(2-hydroxyethyl)pyridin-2-amine; Boc-6-(2-Hydroxyethyl)pyridin-2-ylamine; 402933-56-6; tert-Butyl N-[6-(2-hydroxyethyl)pyridin-2-yl]carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl [6-(2-Hydroxyethyl)Pyridin-2-Yl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.