Description

5-(4-Bromo-Phenoxymethyl)-Furan-2-Carboxylic Acid Methyl Ester is a high-value brominated furan derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular architecture, featuring both a bromophenoxymethyl group and a furan carboxylic ester, makes it an essential building block for constructing complex pharmacologically active molecules. This compound is primarily sought by research institutions and pharmaceutical development companies engaged in the synthesis of novel drug candidates and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug molecules, particularly those targeting central nervous system (CNS) disorders or acting as enzyme inhibitors.
• Agrochemical Research: Used in the development of new active ingredients for crop protection agents, leveraging its halogenated aromatic structure.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers with unique optical or electronic properties.
• Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine atom, enabling the construction of complex biaryl and heteroaryl systems.
• Ligand and Catalyst Development: Utilized as a scaffold for designing novel ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological studies and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	5-(4-Bromo-Phenoxymethyl)-Furan-2-Carboxylic Acid Methyl Ester
CAS No.	402771-33-9
Molecular Formula	C13H11BrO4
Molecular Weight	311.13 g/mol
Synonyms	Methyl 5-[(4-bromophenoxy)methyl]-2-furoate; 5-[(4-Bromophenoxy)methyl]-2-furancarboxylic Acid Methyl Ester; 2-Furancarboxylic acid, 5-[(4-bromophenoxy)methyl]-, methyl ester; Methyl 5-((4-bromophenoxy)methyl)furan-2-carboxylate
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard grade for this intermediate typically meets a purity specification of ≥95% (by HPLC), with comprehensive identity confirmation via spectroscopic methods (NMR, IR, MS). A Certificate of Analysis (COA) detailing purity, identity, and relevant physical data is provided with every shipment. Custom synthesis to higher purity grades (≥98% or ≥99%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.