Description

(+)-Ethyl (S)-2-Amino-4-Cyclohexylbutyrate Hydrochloride CAS NO 402474-20-8 is a high-purity, non-natural amino acid derivative in its hydrochloride salt form, designed for advanced chemical synthesis. This chiral building block is critical for researchers and manufacturers requiring precise stereochemistry and high chemical purity in their processes. It is primarily utilized in the pharmaceutical industry for the research and development of novel active pharmaceutical ingredients (APIs), particularly in peptide mimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Peptidomimetics Research: Serves as a crucial building block for designing and constructing peptide analogs and mimetics with enhanced metabolic stability.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective chemical reactions to introduce specific stereocenters.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Chemical Biology Probes: Utilized in the development of labeled compounds and probes for studying biological mechanisms.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs specializing in complex, custom organic molecules.

Basic Information

Product Name	(+)-Ethyl (S)-2-Amino-4-Cyclohexylbutyrate Hydrochloride
CAS No.	402474-20-8
Molecular Formula	C₁₂H₂₄ClNO₂
Molecular Weight	249.78 g/mol
Synonyms	(S)-2-Amino-4-cyclohexylbutyric acid ethyl ester hydrochloride; Ethyl L-2-amino-4-cyclohexylbutanoate hydrochloride; (S)-Ethyl 2-amino-4-cyclohexylbutanoate HCl; L-2-Amino-4-cyclohexylbutyric acid ethyl ester hydrochloride; ACBC-OEt hydrochloride; (S)-ACBC ethyl ester hydrochloride; (S)-2-Amino-4-cyclohexyl-butyric acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (+)-Ethyl (S)-2-Amino-4-Cyclohexylbutyrate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and impurity profile analysis, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing specific results for identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.