Description

Octanoic Acid, 8-Hydroxy-, 1,1-Dimethylethyl Ester is a specialty organic ester derived from caprylic acid, valued for its unique combination of a medium-chain fatty acid backbone and a sterically hindered tert-butyl ester group. This structure provides enhanced stability and specific reactivity, making it a valuable intermediate for advanced synthesis. It is primarily sought by R&D chemists and process developers in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where the tert-butyl ester serves as a protecting group or imparts specific pharmacokinetic properties.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its lipophilic character for enhanced bioactivity.
• Polymer & Material Science: Serves as a monomer or modifier in the creation of specialty polyesters, coatings, and resins with tailored hydrophobicity and degradation profiles.
• Flavor & Fragrance Chemistry: Acts as a precursor for esters and lactones that contribute to complex flavor and aroma profiles in high-end applications.
• Lubricant & Plasticizer Additive: Incorporated as a stabilizer or co-monomer to improve the performance and longevity of industrial lubricants and polymer plasticizers.
• Organic Synthesis Reagent: Employed in research laboratories for esterification studies, cross-coupling reactions, and as a model compound for method development.

Basic Information

Product Name	Octanoic Acid, 8-Hydroxy-, 1,1-Dimethylethyl Ester
CAS No.	401901-41-5
Molecular Formula	C12H24O3
Molecular Weight	216.32 g/mol
Synonyms	8-Hydroxyoctanoic Acid tert-Butyl Ester; tert-Butyl 8-Hydroxyoctanoate; 1,1-Dimethylethyl 8-Hydroxyoctanoate; 8-Hydroxycaprylic Acid tert-Butyl Ester; TBHOA; Octanoic acid, 8-hydroxy-, tert-butyl ester; tert-Butyl 8-hydroxycaprylate
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system aligned with cGMP principles for pharmaceutical intermediates. Every batch of Octanoic Acid, 8-Hydroxy-, 1,1-Dimethylethyl Ester is analytically verified using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.