Description

(4R)-Boc-4-(4-Methylbenzyl)-Pyr-Obzl CAS NO 401813-50-1 is a high-purity, chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex, biologically active molecules, particularly in the development of new therapeutic agents. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and production of novel active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used in the design and synthesis of peptide analogs and protease inhibitors.
• Asymmetric Synthesis: Serves as a crucial building block in stereoselective chemical reactions to construct complex molecular architectures.
• Medicinal Chemistry: Employed in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.
• Academic Research: Utilized in university and institutional labs for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	(4R)-Boc-4-(4-Methylbenzyl)-Pyr-Obzl
CAS No.	401813-50-1
Molecular Formula	C25H31NO4
Molecular Weight	409.52 g/mol
Synonyms	(4R)-1-(tert-Butoxycarbonyl)-4-[(4-methylphenyl)methyl]-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester; tert-Butyl (4R)-4-[(4-methylphenyl)methyl]-2,5-dihydro-1H-pyrrole-1-carboxylate 2-carboxylic acid benzyl ester; (R)-1-Boc-4-(4-methylbenzyl)-3,4-dihydro-2H-pyrrole-5-carboxylic acid benzyl ester; Boc-4-(4-Methylbenzyl)-D-Pro-Obzl; (R)-Boc-4-(p-Methylbenzyl)-pyrrolidine-2-carboxylic acid benzyl ester; (4R)-Boc-4-(4-Methylbenzyl)-2,5-dihydro-1H-pyrrole-2-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our (4R)-Boc-4-(4-Methylbenzyl)-Pyr-Obzl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.