Description

5-Chloro-6-(Piperazin-1-Yl)Nicotinic Acid Ethyl Ester is a high-value pharmaceutical intermediate and versatile chemical building block. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel drug candidates. It is primarily needed by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical producers engaged in the development of active pharmaceutical ingredients (APIs) and other specialty molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced pesticides and herbicides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and enzyme functions.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of specialty chemicals for various industrial applications.
• Academic Research: Used in university and institutional labs for organic synthesis projects and methodological development.

Basic Information

Product Name	5-Chloro-6-(Piperazin-1-Yl)Nicotinic Acid Ethyl Ester
CAS No.	401566-70-9
Molecular Formula	C12H16ClN3O2
Molecular Weight	269.73 g/mol
Synonyms	Ethyl 5-chloro-6-(piperazin-1-yl)nicotinate; 5-Chloro-6-piperazin-1-yl-pyridine-3-carboxylic acid ethyl ester; 401566-70-9; 5-Chloro-6-(1-piperazinyl)-3-pyridinecarboxylic acid ethyl ester; Ethyl 5-chloro-6-(1-piperazinyl)nicotinate; Nicotinic acid, 5-chloro-6-(1-piperazinyl)-, ethyl ester; 3-Pyridinecarboxylic acid, 5-chloro-6-(1-piperazinyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloro-6-(Piperazin-1-Yl)Nicotinic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.