Description

1,3-Dioxolane-4-Carboxylicacid,5-Methyl-,Methylester,(4R,5S)-(9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters as a key intermediate in the production of complex pharmaceutical actives and fine chemicals, where its specific stereochemistry is critical for biological activity and process efficiency. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drugs, catalysts, and high-value materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereospecific herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring precise stereochemical control.
• Material Science Research: Investigated as a monomer or modifying agent for synthesizing novel polymers with specific optical or mechanical properties.
• Process Chemistry Development: Utilized in route scouting and optimization for scalable manufacturing of stereochemically pure compounds.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxylicacid,5-Methyl-,Methylester,(4R,5S)-(9Ci)
CAS No.	401480-01-1
Molecular Formula	C7H10O5
Molecular Weight	174.15 g/mol
Synonyms	(4R,5S)-5-Methyl-1,3-dioxolane-4-carboxylic acid methyl ester; Methyl (4R,5S)-5-methyl-1,3-dioxolane-4-carboxylate; (4R,5S)-5-Methyl-1,3-dioxolane-4-carboxylic acid methyl ester; (4R-cis)-5-Methyl-1,3-dioxolane-4-carboxylic Acid Methyl Ester; Methyl (4R,5S)-5-methyl-1,3-dioxolan-4-carboxylate; 1,3-Dioxolane-4-carboxylic acid, 5-methyl-, methyl ester, (4R,5S)-; (4R,5S)-5-Methyl-1,3-dioxolan-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxylicacid,5-Methyl-,Methylester,(4R,5S)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.