Description

tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Piperidine-1-Carboxylate is a high-purity pharmaceutical intermediate and building block of significant importance in modern drug discovery. This compound serves as a key synthon for the development of novel therapeutic agents, particularly kinase inhibitors. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Drug Discovery Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization campaigns.
• Biochemical Research: Employed as a reference standard or probe compound in biochemical and pharmacological assays.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing custom APIs and novel chemical entities.
• Academic Research: Utilized in university and institutional labs for developing new synthetic methodologies and exploring novel heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Piperidine-1-Carboxylate
CAS No.	400801-83-4
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-(7-azaindol-3-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine; 4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine-1-carboxylate; 4-(7-Azaindol-3-yl)-1-N-Boc-piperidine; 400801-83-4; 1-Boc-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)piperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Piperidine-1-Carboxylate adheres to stringent quality protocols suitable for pharmaceutical R&D applications. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.