Description

5-Methanesulfonyl-3-(4-Trifluoromethyl-Phenyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine is a high-value, heterocyclic organic compound featuring a pyrazolopyridine core with a trifluoromethylphenyl substituent and a methanesulfonyl group. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate for the research and development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D organizations and fine chemical manufacturers engaged in drug discovery programs, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Drug Discovery Research: Used as a core scaffold or precursor for developing compounds with potential biological activity in high-throughput screening.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a critical intermediate in the multi-step production of complex target molecules for preclinical and clinical studies.
• Chemical Biology Probe Development: Utilized in the creation of specialized molecular tools for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for methodological development and the exploration of new heterocyclic chemistry.

Basic Information

Product Name	5-Methanesulfonyl-3-(4-Trifluoromethyl-Phenyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine
CAS No.	400797-90-2
Molecular Formula	C15H14F3N3O2S
Molecular Weight	357.35 g/mol
Synonyms	5-(Methylsulfonyl)-3-[4-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; 3-(4-Trifluoromethylphenyl)-5-methanesulfonyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine; 4,5,6,7-Tetrahydro-3-(4-trifluoromethylphenyl)-1H-pyrazolo[4,3-c]pyridine-5-methanesulfonate; Pyrazolo[4,3-c]pyridine intermediate 400797-90-2; CAS 400797-90-2
EINECS	Contact for details

Quality Control

Our production of 5-Methanesulfonyl-3-(4-Trifluoromethyl-Phenyl)-4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our commitment to cGMP principles and traceability ensures the material is suitable for demanding pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.