Description

1H-Pyrazolo[3,4-B]Pyridin-4(7H)-One is a high-value heterocyclic organic compound, specifically a fused pyrazolopyridinone derivative, serving as a critical advanced pharmaceutical intermediate. Its core value lies in its versatile scaffold, which is essential for the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. This compound is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and development, particularly for creating kinase inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors.
• Drug Discovery Research: Core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis: Used in organic synthesis to construct complex nitrogen-containing heterocycles for various applications.
• Biochemical Research: Potential tool compound for probing biological pathways and enzyme functions in academic and industrial R&D.
• Agrochemical Development: Intermediate in the research and development of new crop protection agents.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridin-4(7H)-One
CAS No.	49834-67-5
Molecular Formula	C6H5N3O
Molecular Weight	135.12 g/mol
Synonyms	4(7H)-Pyrazolo[3,4-b]pyridinone; 7H-Pyrazolo[3,4-b]pyridin-4-one; 1H-Pyrazolo[3,4-b]pyridin-4-ol; 4-Hydroxy-1H-pyrazolo[3,4-b]pyridine; 4-Oxo-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine; Pyrazolo[3,4-b]pyridin-4(7H)-one; 49834-67-5 (CAS RN)
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridin-4(7H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with the stringent requirements of pharmaceutical R&D and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.