Description

1,4-Dioxaspiro[4.5]Decan-7-Amine is a versatile spirocyclic amine compound featuring a protected ketone functionality. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical sectors for the construction of complex molecular architectures. The compound's reactivity profile allows for selective transformations, enabling the efficient synthesis of target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of novel herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex natural products, ligands, and functional materials.
• Chemical Research: Employed in methodological studies for ring-opening reactions, amination processes, and the synthesis of heterocyclic compounds.
• Fine Chemical Production: Acts as an intermediate in the custom synthesis of specialty chemicals for electronics and material science applications.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decan-7-Amine
CAS No.	49672-69-7
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	7-Amino-1,4-dioxaspiro[4.5]decane; 1,4-Dioxaspiro[4.5]decan-7-amine; 7-Amino-1,4-dioxaspiro[4.5]decane; Spiro[1,3-dioxolane-2,1'-cyclohexan]-4'-amine; 4'-Aminospiro[1,3-dioxolane-2,1'-cyclohexane]; 1,4-Dioxaspiro[4,5]decan-7-ylamine; 7-Amino-1,4-dioxaspiro[4,5]decane
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Decan-7-Amine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high purity and consistent quality suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.