Description

2-Bromo-6-(2-Methyl-1,3-Dioxolan-2-Yl)Pyridine is a versatile brominated pyridine derivative featuring a protected carbonyl group in the form of a dioxolane ring. This compound serves as a critical advanced pharmaceutical intermediate (API) and a valuable building block in organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of complex molecules for the pharmaceutical and agrochemical sectors. The specific molecular architecture makes it a key precursor for constructing heterocyclic frameworks with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine core.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis, including those used in cross-coupling reactions like Suzuki-Miyaura couplings.
• Material Science Precursor: Acts as a monomer or functionalizing agent in the synthesis of advanced organic materials and liquid crystals.
• Academic & Contract Research: Essential for methodology development and exploring new synthetic routes in academic laboratories and CROs (Contract Research Organizations).
• Fine Chemical Production: Serves as a starting material for the manufacture of other high-value, specialty brominated compounds.

Basic Information

Item	Details
Product Name	2-Bromo-6-(2-Methyl-1,3-Dioxolan-2-Yl)Pyridine
CAS No.	49669-14-9
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	2-Bromo-6-(2-methyl-1,3-dioxolan-2-yl)pyridine; 6-Bromo-2-(2-methyl-1,3-dioxolan-2-yl)pyridine; 2-(2-Bromopyridin-6-yl)-2-methyl-1,3-dioxolane; 2-Methyl-2-(6-bromo-2-pyridyl)-1,3-dioxolane; Pyridine, 2-bromo-6-(2-methyl-1,3-dioxolan-2-yl)-; (6-Bromo-2-pyridinyl)-2-methyl-1,3-dioxolane
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-6-(2-Methyl-1,3-Dioxolan-2-Yl)Pyridine is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets high-purity requirements suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.