Description

2-Chloromethylpyridine-5-Carboxylic Acid Methyl Ester is a versatile and high-value pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a reactive chloromethyl group and an ester moiety, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the pyridine core is a common bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of other high-value fine chemicals and specialty materials.

Basic Information

Product Name	2-Chloromethylpyridine-5-Carboxylic Acid Methyl Ester
CAS No.	49668-90-8
Molecular Formula	C9H8ClNO2
Molecular Weight	197.62 g/mol
Synonyms	Methyl 2-(chloromethyl)nicotinate; Methyl 2-(chloromethyl)pyridine-5-carboxylate; 5-(Methoxycarbonyl)-2-pyridinemethanol chloride; 2-Chloromethyl-5-pyridinecarboxylic acid methyl ester; 2-(Chloromethyl)nicotinic acid methyl ester; 2-Pyridinecarboxylic acid, 2-(chloromethyl)-, methyl ester; Nicotinic acid, 2-(chloromethyl)-, methyl ester
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our chemical intermediates. Production follows current Good Manufacturing Practices (cGMP) where applicable, and every batch is analyzed to ensure consistency and high purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.