Description

3,3A,5,6,7,7A-Hexahydro-2,5-Methanofuro[3,2-B]Pyridine-4(2H)-Carboxylic Acid Ethyl Ester is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound, with CAS number 49656-60-2, serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and central nervous system disorders.
• Organic Synthesis Reagent: Used in advanced synthetic methodologies, including cycloadditions and ring-forming reactions, to create novel heterocyclic compounds.
• Agrochemical Research: Serves as a precursor in the development of new active ingredients for crop protection products.
• Material Science: Potential use in the synthesis of specialty polymers and ligands for catalytic systems.
• Academic & Contract Research: Essential for research institutions and CROs (Contract Research Organizations) exploring new chemical entities and reaction pathways.

Basic Information

Item	Detail
Product Name	3,3A,5,6,7,7A-Hexahydro-2,5-Methanofuro[3,2-B]Pyridine-4(2H)-Carboxylic Acid Ethyl Ester
CAS No.	49656-60-2
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	Ethyl 3,3a,5,6,7,7a-hexahydro-2,5-methanofuro[3,2-b]pyridine-4(2H)-carboxylate; 2,5-Methanofuro[3,2-b]pyridine-4(2H)-carboxylic acid, 3,3a,5,6,7,7a-hexahydro-, ethyl ester; Ethyl hexahydro-2,5-methanofuro[3,2-b]pyridine-4-carboxylate; 49656-60-2; Furo[3,2-b]pyridine derivative
EINECS	Contact for details

Quality Control

Our 3,3A,5,6,7,7A-Hexahydro-2,5-Methanofuro[3,2-B]Pyridine-4(2H)-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Grade)
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.